The term “terminal lucidity” refers to an unexpected surge of mental clarity in confused or even unconscious patients shortly before death. This phenomenon was described many times, particularly in the 19th century, but has hardly been discussed in recent decades. In 2009, Michael Nahm coined the term “terminal lucidity” to help bring it back to the attention of physicians and scientists.
However, unexpected episodes of mental clarity do not only occur before death. Co-authors and I have coined the related term “paradoxical lucidity” for cases in which patients with severe neurological conditions show an unexpected surge of mental clarity also at times that precede their death considerably. Since then, many scientists, particularly in the field of dementia research, have begun to study terminal and paradoxical lucidity. These studies could shed light on our understanding of the interplay between the human mind and brain and lead to the development of new therapies.